{"id":7154,"date":"2023-11-02T16:18:16","date_gmt":"2023-11-02T13:18:16","guid":{"rendered":"https:\/\/kayhanturan.com\/uncategorized\/what-is-hydrogel-liquid-knee-replacement\/"},"modified":"2025-01-28T18:11:42","modified_gmt":"2025-01-28T15:11:42","slug":"what-is-hydrogel","status":"publish","type":"post","link":"https:\/\/kayhanturan.com\/en\/blog\/what-is-hydrogel\/","title":{"rendered":"What is Hydrogel (Liquid Knee Replacement)?"},"content":{"rendered":"\n
Individuals with osteoarthritis typically experience symptoms such as pain, swelling, limited mobility, and joint deformities. These symptoms can significantly impact daily life, making activities like climbing stairs, walking long distances, or squatting challenging and painful.<\/p>\n\n\n\n
Osteoarthritis is a joint disease caused by the gradual wear and tear of the cartilage tissue over time. Cartilage is a smooth and elastic tissue that cushions the ends of bones in joints. This cartilage enables smooth joint movement and prevents bones from rubbing against each other. When the cartilage deteriorates, bones can come into contact, leading to pain and inflammation.<\/p>\n\n\n\n
Osteoarthritis is the thinning and wear and tear of cartilaginous tissue, causing the bones to rub against each other and causing pain. Risk factors for knee arthritis include genetic predisposition, obesity, prior knee injuries, and repetitive stress or overuse of the joint. While more common in older adults, osteoarthritis can also affect younger individuals.<\/p>\n\n\n\n
Although there is no definitive cure for knee arthritis, various treatments aim to alleviate pain, improve mobility, and enhance quality of life. These include medications, physical therapy, knee braces, intra-articular injections, and, in severe cases, surgical interventions (when necessary).<\/p>\n\n\n\n
One emerging treatment option is intra-articular hydrogel injections<\/strong>, scientifically known as polyacrylamide hydrogel (PAAG)<\/strong>. This method, sometimes referred to as \u201cliquid knee replacement<\/strong>,\u201d involves injecting a gel-like substance into the joint to provide cushioning and reduce friction between bones. While promising, its long-term efficacy and safety are still being researched.<\/p>\n\n\n\n Read the rest of our article to find out how the hydrogel injection<\/strong> is applied and whether it really has an effect.<\/p>\n\n\n\n Table of Contents:<\/p>\n\n\n\n Choosing the most appropriate treatment for knee osteoarthritis depends on several key factors, including the stage of the disease, the patient\u2019s age, general health, pain severity, lifestyle, and personal preferences. These factors are carefully considered by the doctor and the patient to develop an individualized treatment plan.<\/p>\n\n\n\n All these factors must be assessed through open discussions between the patient and their doctor. By considering each individual’s unique needs and circumstances, the most suitable osteoarthritis treatment plan can be determined.<\/p>\n\n\n\n Hydrogels<\/strong>, which are used as a new method in the treatment of knee joint arthritis, were first introduced in 1960. Their first use was in the production of contact lenses. Hydrogels are smart biomaterials that can absorb large amounts of water and thus exhibit swelling properties.<\/p>\n\n\n\n The formation of hydrogel<\/strong> involves the crosslinking of polymer chains to create a water-absorbent, gel-like structure. Because of their high water content, hydrogels closely resemble living tissue, making them highly biocompatible and less likely to be perceived as foreign bodies when injected into the body.<\/p>\n\n\n\n Hydrogels’ compatibility with biological systems has made them indispensable in medicine, but their applications extend beyond this field to include pharmacy, cosmetics, agriculture, chemistry, and food technology. Their versatility stems from their ability to adapt to various environments, absorb water, and provide structural support.<\/p>\n\n\n\n While hydrogels have many applications, the most important medical hydrogel<\/strong> applications are listed below:<\/p>\n\n\n\n Hydrogels are also finding increasing application in the treatment of knee arthritis. Their ability to act as a cushion and reduce friction between bones has led to their use in intra-articular injections worldwide. However, questions remain about their long-term effectiveness and duration of action in treating knee arthritis: How long does hydrogel last<\/strong>? These issues will be explored in the following sections.<\/p>\n\n\n\n The use of polyacrylamide (PAAG) hydrogel knee injections<\/strong> represents a novel approach to the treatment of knee osteoarthritis.<\/p>\n\n\n\n Since the hydrogel is compatible with body biology, it can be injected into the knee joint as a sterile gel. Hydrogel joint injections<\/strong> consist of 97.5% sterile water and 2.5% polyacrylamide. The polyacrylamide component prevents biodegradation, ensuring that the hydrogel remains effective over time without being absorbed or broken down by the body.<\/p>\n\n\n\n Injectable hydrogel<\/strong> is administered into the knee joint cavity and integrates with the synovial tissue. Thus, the synovial membrane thickens. And what does that mean? The knee joint is lined with a special thin membrane (synovium) made of small synovial cells. The synovial membrane is a thin layer of tissue that lines the joint and produces synovial fluid, the natural lubricant that enables smooth joint movement. In osteoarthritis, this membrane often becomes inflamed, a condition known as synovitis, which contributes to pain, stiffness, and reduced mobility.<\/p>\n\n\n\n Hydrogel injections for knees<\/strong> can help to combat these issues by forming a protective, stable layer over the surface of the synovial membrane. This layer reduces inflammation and enhances the production of synovial fluid, creating a more favorable environment for joint movement.<\/p>\n\n\n\n Within a few weeks of injection, the hydrogel adheres to the synovial membrane and integrates into the surrounding joint capsule, acting as a hydrogel scaffold<\/strong>. In other words, it forms a cushion within the joint, supporting load-bearing functions and strengthening the joint capsule. Additionally, hydrogel properties<\/strong> improve the elasticity of the joint, potentially enhancing mobility and reducing discomfort.<\/p>\n\n\n\n While hydrogel treatment offers several benefits, including reduced inflammation and improved joint function, it is important to note that this method is relatively new. Clinical studies are ongoing to evaluate its long-term safety, efficacy, and durability. However, early results are promising, making hydrogel injections an exciting option for individuals with knee osteoarthritis.<\/p>\n\n\n\n Hydrogel injection is a minimally invasive procedure performed in a clinical setting under sterile conditions. The process involves injecting the hydrogel directly into the knee joint to provide cushioning and improve joint function. Below are the steps typically followed during the procedure:<\/p>\n\n\n\n Preparation:<\/strong> The patient is given a single dose of antibiotics before the procedure to minimize the risk of infection. A small amount of local anesthetic is administered to numb the area and reduce any discomfort during the injection.<\/p>\n\n\n\n Ultrasound Guidance:<\/strong> An ultrasound scan may be performed prior to the injection to identify the most appropriate injection site and evaluate the level of fluid in the knee joint.<\/p>\n\n\n\n Drainage of Excess Fluid: <\/strong>If there is significant fluid buildup in the knee joint (a condition known as effusion), the excess fluid is drained (aspirated) using a syringe. This step reduces joint pressure and allows the hydrogel to integrate more effectively with the joint.<\/p>\n\n\n\n Injection of Hydrogel: <\/strong>A sterile needle is used to inject the hydrogel directly into the synovial cavity. The hydrogel is delivered in a controlled manner to ensure even distribution and optimal cushioning effects. The procedure is typically quick, taking only a few minutes to complete.<\/p>\n\n\n\n After the hydrogel injection, the patient should be monitored for 10-15 minutes to ensure there are no immediate side effects, such as allergic reactions or excessive swelling. After the local anesthetic wears off, mild joint pain and swelling may occur. In such cases, over-the-counter painkillers like acetaminophen or NSAIDs (e.g., ibuprofen) may be recommended to manage discomfort. Applying an ice pack to the knee for 15\u201320 minutes at a time can also help reduce swelling.<\/p>\n\n\n\n Patients are advised to rest the knee for at least 2\u20133 days following the injection. Strenuous activities, such as running, long walks, or heavy lifting, should be avoided to minimize the risk of inflammation or flare-ups. Gradual resumption of normal activities is encouraged, but any activity that causes significant pain should be avoided.<\/p>\n\n\n\n The benefit of the injection usually becomes noticeable around 4 weeks after administration, with maximum effectiveness often achieved within 12 weeks. Since the hydrogel is not broken down by the body, it may provide prolonged pain relief and improved joint function compared to other treatments.<\/p>\n\n\n\n A holistic approach<\/strong> is adopted in the treatment of knee arthritis. Some other interventions, such as tailored exercise programs, physical therapy, bracing, and weight management treatment methods, are used together.<\/p>\n\n\n\n Patients should follow their orthopedic doctor\u2019s and physiotherapist\u2019s advice for ongoing care and schedule follow-up appointments to monitor progress. This integrated approach helps optimize long-term results and improves overall quality of life.<\/p>\n\n\n\n Studies indicate that polyacrylamide (PAAG) hydrogel for knees<\/strong> is generally well received by patients and considered safe. However, as with any medical procedure, hydrogel injections can be associated with certain side effects. While most are mild and temporary, some may require medical attention. Possible hydrogel injection side effects<\/strong> are as follows:<\/p>\n\n\n\n Most side effects are short-lived and manageable. However, if you experience any of the following, contact a healthcare professional immediately:<\/p>\n\n\n\n By following post-procedure care instructions and staying in communication with your healthcare provider, the risks of side effects can be minimized, and the benefits of the hydrogel injection are maximized.<\/p>\n\n\n\n Although hydrogel injection is a treatment that can benefit many patients, it may not be suitable for everyone. People with the following conditions are advised not to undergo hydrogel injection treatment:<\/p>\n\n\n\n People experiencing these and similar conditions should consult their doctor for appropriate treatment options and alternative therapies.<\/p>\n\n\n\n With ongoing advancements in the treatment of knee osteoarthritis, there is growing interest in non-surgical methods, such as hydrogel injections. These methods offer patients and physicians hope for effective pain relief and improved joint function while delaying or avoiding surgical intervention. Among these, hydrogel therapy has gained attention as a minimally invasive option.<\/p>\n\n\n\n Current studies and clinical experience suggest that hydrogel injections may reduce pain and enhance joint mobility for certain patients with knee osteoarthritis. Preliminary data indicate that the effects of this treatment can last up to three years, making it a promising option for short- to medium-term management. However, longer-term studies (spanning five and ten years) are still underway to evaluate its sustained effectiveness and safety.<\/p>\n\n\n\n While hydrogel therapy<\/strong> shows promise, it is important to note that its efficacy can vary from patient to patient. In some cases, the treatment may postpone the need for surgical intervention, but it may not eliminate the necessity of surgery in the long term. Additionally, more extensive research is needed to understand better its long-term effects, potential side effects, and the specific patient populations most likely to benefit.<\/p>\n\n\n\n Ultimately, there is no \u201cone-size-fits-all\u201d solution for treating osteoarthritis of the knee. The best treatment approach depends on the patient\u2019s individual condition, severity of symptoms, and overall health. Hydrogel therapy<\/strong> can be an effective option for managing symptoms in some patients, but it should be considered as part of a comprehensive treatment plan. <\/p>\n\n\n\nFactors Affecting Method Selection in Knee Osteoarthritis Treatment<\/h2>\n\n\n\n
What is Hydrogel? What are Hydrogels Used for?<\/h2>\n\n\n\n
Hydrogel Treatment for Knee Osteoarthritis<\/h2>\n\n\n\n
How is Hydrogel Injection Applied?<\/h2>\n\n\n\n
After Hydrogel Injection<\/h2>\n\n\n\n
Are There Any Hydrogel Injection Side Effects?<\/h2>\n\n\n\n
Who is not Suitable for Hydrogel Injection?<\/h2>\n\n\n\n
Conclusion: Is Hydrogel Therapy for Knee Osteoarthritis Really Effective?<\/h2>\n\n\n\n